The Boston Bruins suffered their 2nd-straight loss, falling to the Vegas Golden Knights 6-5 on Thursday night.
Tanner Jeannot, Nikita Zadorov, David Pastrnak, Mark Kastelic, and Michael Eyssimont scored goals for the Bruins.
Cole Reinhardt and Tomas Hertl also scored, with Hertl's goal ending the Bruins' streak of 14 successful penalty kills to open the season.
Karlsson's goals came on a short-handed opportunity and a power play.
Dorofeyev tied Ottawa's Shane Pinto for the league lead in goals, and Eichel extended his points streak to five games with his fifth goal and an assist.
Author's summary: Bruins lose to Golden Knights 6-5.