About one in 10 Americans will experience knee pain, swelling, and stiffness, with the most common diagnosis being osteoarthritis (OA) of the knee.
OA of the knee is a complex condition caused by multiple factors, including inflammation and wear and tear on the joints, leading to the erosion of the cartilage "cushion" and painful bone-on-bone contact.
Currently, there is no cure for OA of the knee, with short-term measures such as oral pain medications, physical therapy, or steroid injections providing temporary relief.
Longer-term alternatives to surgery are limited, especially as the condition worsens, with age and obesity being risk factors.
Doron Therapeutics has begun a Phase 3 study of a treatment for osteoarthritis of the knee.
No cure yet for OA of the knee.
Author's summary: Doron Therapeutics starts Phase 3 study for OA knee treatment.