Model Establishes Framework for Designing Drugs to Prevent Neurodegenerative Disorders
An analytical model describes the aggregation of amyloid-forming proteins via lipid-mediated interactions.
Many neurodegenerative disorders, such as Parkinson’s disease, share the hallmark of functional proteins forming deposits known as amyloid fibrils in a process that can be modulated by the presence of lipids.
A theoretical model of lipid-induced aggregation has been developed with the aim of creating a tool that can be used to inform the design of anti-aggregation drugs.
The analytical model accounts for lipid-mediated interactions in terms of kinetic equations for the surface coverage of monomers and aggregates.
Model establishes framework for designing drugs to prevent neurodegenerative disorders.
Author's summary: A new model helps design drugs for neurodegenerative disorders.
More News
- How to teach Dragon Ascent to Rayquaza - Pokémon Go? - TechStory
- Nico Paz decisive: Juve loses in Como before Bernabéu visit
- YOUR SUNDAY READING LIST: Emergency Nudity, ICE on Parade, and Portland's Hero Frogs
- Como 2-0 Juventus: Nico Paz puts toothless Old Lady to the torch
- Lawson dismisses Tsunoda’s claims of deliberate blocking in Austin
- ICC dismisses Israel's appeal against arrest warrants for Netanyahu, Gallant
- Juventus player ratings vs Como: A day to forget for Conceicao -
- Keanu Reeves Just Responded to Those Alexandra Grant Marriage Rumors